Haematopoietic protein tyrosine phosphatase (HePTP) phosphorylation by cAMP-dependent protein kinase in T-cells: dynamics and subcellular location.

The HePTP (haematopoietic protein tyrosine phosphatase) is a negative regulator of the ERK2 (extracellular signal-regulated protein kinase 2) and p38 MAP kinases (mitogen-activated protein kinases) in T-cells. This inhibitory function requires a physical association of HePTP through an N-terminal KI...

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Autores principales: Nika, Konstantina, Hyunh, Huong, Williams, Scott, Paul, Surojit, Bottini, Nunzio, Taskén, Kjetil, Lombroso, Paul J, Mustelin, Tomas
Formato: Artigo
Lenguaje:Inglês
Publicado: 2004
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223964/
https://ncbi.nlm.nih.gov/pubmed/14613483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031244
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