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Mitochondrial cytochrome c release may occur by volume-dependent mechanisms not involving permeability transition.

The mechanisms regulating mitochondrial outer-membrane permeabilization and the release of cytochrome c during apoptosis remain controversial. In the present study, we show in an in vitro model system that the release of cytochrome c may occur via moderate modulation of mitochondrial volume, irrespe...

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Main Authors: Gogvadze, Vladimir, Robertson, John D, Enoksson, Mari, Zhivotovsky, Boris, Orrenius, Sten
格式: Artigo
語言:Inglês
出版: 2004
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223940/
https://ncbi.nlm.nih.gov/pubmed/14629197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031193
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