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Oligomeric BAX induces mitochondrial permeability transition and complete cytochrome c release without oxidative stress

In the present study, we investigated the mechanism of cytochrome c release from isolated brain mitochondria induced by recombinant oligomeric BAX (BAX(oligo)). We found that BAX(oligo) caused a complete release of cytochrome c in a concentration- and time-dependent manner. The release was similar t...

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Bibliographische Detailangaben
Hauptverfasser: Li, Tsyregma, Brustovetsky, Tatiana, Antonsson, Bruno, Brustovetsky, Nickolay
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613194/
https://ncbi.nlm.nih.gov/pubmed/18771651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2008.08.002
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