BAX insertion, oligomerization, and outer membrane permeabilization in brain mitochondria: role of permeability transition and SH-redox regulation

BAX cooperates with truncated BID (tBID) and Ca(2+) in permeabilizing the outer mitochondrial membrane (OMM) and releasing mitochondrial apoptogenic proteins. The mechanisms of this cooperation are still unclear. Here we show that in isolated brain mitochondria, recombinant BAX readily self-integrat...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Brustovetsky, Tatiana, Li, Tsyregma, Yang, Youyun, Zhang, Jiang-Ting, Antonsson, Bruno, Brustovetsky, Nickolay
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933961/
https://ncbi.nlm.nih.gov/pubmed/20655869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2010.07.006
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