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Mitochondrial cytochrome c release may occur by volume-dependent mechanisms not involving permeability transition.
The mechanisms regulating mitochondrial outer-membrane permeabilization and the release of cytochrome c during apoptosis remain controversial. In the present study, we show in an in vitro model system that the release of cytochrome c may occur via moderate modulation of mitochondrial volume, irrespe...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2004
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1223940/ https://ncbi.nlm.nih.gov/pubmed/14629197 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031193 |
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