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Processed caspase-2 can induce mitochondria-mediated apoptosis independently of its enzymatic activity
The mechanism by which caspase-2 executes apoptosis remains obscure. Recent findings indicate that caspase-2 is activated early in response to DNA-damaging antineoplastic agents and may be important for the engagement of the mitochondrial apoptotic pathway. We demonstrate here that fully processed c...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1299073/ https://ncbi.nlm.nih.gov/pubmed/15153933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400153 |
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