Učitavanje...
Protein tyrosine phosphatase 1B participates in the down-regulation of erythropoietin receptor signalling.
Erythropoietin (EPO) is the principal hormone regulating the proliferation of erythroid precursors and their differentiation into erythrocytes. Binding of ligand to the cell-surface EPO-R (EPO receptor) induces dimerization and JAK2 (Janus kinase 2)-mediated tyrosine phosphorylation of the receptor....
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| Glavni autori: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2004
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1223869/ https://ncbi.nlm.nih.gov/pubmed/14527337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031420 |
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