Ceramide and glutathione define two independently regulated pathways of cell death initiated by p53 in Molt-4 leukaemia cells.

The tumour suppressor p53 induces cell death by launching several pathways that are either dependent on or independent of gene transcription. Accumulation of the sphingolipid ceramide and reactive oxygen species are among these pathways. Crossregulation of these two pathways is possible owing to the...

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Detalhes bibliográficos
Main Authors: El-Assaad, Wissal, Kozhaya, Lina, Araysi, Sawsan, Panjarian, Shoghag, Bitar, Fadi F, Baz, Elizabeth, El-Sabban, Marwan E, Dbaibo, Ghassan S
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223811/
https://ncbi.nlm.nih.gov/pubmed/12967322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030888
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