IL-1 stimulates ceramide accumulation without inducing apoptosis in intestinal epithelial cells.

BACKGROUND: In inflammatory bowel disease (IBD), cytokine levels (such as interleukin-1 (IL-1)) are elevated. We have shown previously that IL-1 activates phospholipid signaling pathways in intestinal epithelial cells (EEC), leading to increased ceramide levels. AIM: To determine whether ceramide in...

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Detalhes bibliográficos
Main Authors: Homaidan, Fadia R, El-Sabban, Marwan E, Chakroun, Iman, El-Sibai, Mirvat, Dbaibo, Ghassan S
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1781644/
https://ncbi.nlm.nih.gov/pubmed/11926594
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