Nalaganje...

A functional study on polymorphism of the ATP-binding cassette transporter ABCG2: critical role of arginine-482 in methotrexate transport.

Overexpression of the ATP-binding cassette transporter ABCG2 reportedly causes multidrug resistance, whereas altered drug-resistance profiles and substrate specificity are implicated for certain variant forms of ABCG2. At least three variant forms of ABCG2 have been hitherto documented on the basis...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Mitomo, Hideyuki, Kato, Ryo, Ito, Akiko, Kasamatsu, Shiho, Ikegami, Yoji, Kii, Isao, Kudo, Akira, Kobatake, Eiry, Sumino, Yasuhiro, Ishikawa, Toshihisa
Format: Artigo
Jezik:Inglês
Izdano: 2003
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223553/
https://ncbi.nlm.nih.gov/pubmed/12741957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030150
Oznake: Označite
Brez oznak, prvi označite!