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Effect of spermine synthase on the sensitivity of cells to anti-tumour agents.

The role of spermine in the sensitivity of cells to various established and experimental anti-tumour agents was examined, using paired cell lines that possess or lack spermine synthase. All spermine-synthase-deficient cells had no detectable spermine, and elevated spermidine, content. Spermine conte...

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Detalhes bibliográficos
Main Authors: Ikeguchi, Yoshihiko, Mackintosh, Caroline A, McCloskey, Diane E, Pegg, Anthony E
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223546/
https://ncbi.nlm.nih.gov/pubmed/12737625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030246
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