Complexes between the nonsense-mediated mRNA decay pathway factor human upf1 (up-frameshift protein 1) and essential nonsense-mediated mRNA decay factors in HeLa cells.

mRNAs harbouring premature translation-termination codons are usually degraded by the nonsense-mediated mRNA decay (NMD) pathway. Human up-frameshift protein 1 (Hupf1) is an NMD factor that is conserved between yeast and mammals. To isolate cellular complexes that are formed with Hupf1 and to explor...

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Autors principals: Schell, Thomas, Köcher, Thomas, Wilm, Matthias, Seraphin, Bertrand, Kulozik, Andreas E, Hentze, Matthias W
Format: Artigo
Idioma:Inglês
Publicat: 2003
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223536/
https://ncbi.nlm.nih.gov/pubmed/12723973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021920
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