c-Myc potentiates the mitochondrial pathway of apoptosis by acting upstream of apoptosis signal-regulating kinase 1 (Ask1) in the p38 signalling cascade.

Lignende værker

• Role of Apoptosis Signal-regulating Kinase 1 (ASK1) as an Activator of the GAPDH-Siah1 Stress-Signaling Cascade
  af: Tristan, Carlos A., et al.
  Udgivet: (2015)
• Involvement of p38 in Apoptosis-associated Membrane Blebbing and Nuclear Condensation
  af: Deschesnes, Réna G., et al.
  Udgivet: (2001)
• Peroxiredoxin-2 Protects against 6-Hydroxydopamine-Induced Dopaminergic Neurodegeneration via Attenuation of the Apoptosis Signal-Regulating Kinase (ASK1) Signaling Cascade
  af: Hu, Xiaoming, et al.
  Udgivet: (2011)
• Discovery of CNS-Penetrant Apoptosis Signal-Regulating Kinase 1 (ASK1) Inhibitors
  af: Xin, Zhili, et al.
  Udgivet: (2020)
• Signaling cascades transmit information downstream and upstream but unlikely simultaneously
  af: Catozzi, Simona, et al.
  Udgivet: (2016)