c-Myc potentiates the mitochondrial pathway of apoptosis by acting upstream of apoptosis signal-regulating kinase 1 (Ask1) in the p38 signalling cascade.

Cell transformation by growth-promoting oncoproteins renders cells extremely sensitive to apoptosis through an unknown mechanism affecting the mitochondrial pathway of apoptosis. We have shown previously that sensitization to apoptosis also correlated with the activation of the stress-activated prot...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Desbiens, Katia M, Deschesnes, Réna G, Labrie, Mireille M, Desfossés, Yan, Lambert, Herman, Landry, Jacques, Bellmann, Kerstin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2003
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223429/
https://ncbi.nlm.nih.gov/pubmed/12646044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021565
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