Peroxiredoxin-2 Protects against 6-Hydroxydopamine-Induced Dopaminergic Neurodegeneration via Attenuation of the Apoptosis Signal-Regulating Kinase (ASK1) Signaling Cascade

The peroxiredoxin (PRX) family of antioxidant enzymes helps maintain the intracellular reducing milieu and suppresses apoptosis in non-neuronal cells. However, whether PRX can inhibit neuronal apoptosis through specific signaling mechanisms remains poorly understood. Induction of PRX2, the most abun...

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Autors principals: Hu, Xiaoming, Weng, Zhongfang, Chu, Charleen T., Zhang, Lili, Cao, Guodong, Gao, Yanqin, Signore, Armando, Zhu, Jianhui, Hastings, Teresa, Greenamyre, J. Timothy, Chen, Jun
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2011
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078571/
https://ncbi.nlm.nih.gov/pubmed/21209210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4589-10.2011
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