Glucagon-like peptide 1 and fatty acids amplify pulsatile insulin secretion from perifused rat islets.

Glucose-induced insulin secretion from isolated, perifused rat islets is pulsatile with a period of about 5-10 min, similar to the insulin oscillations that are seen in healthy humans but which are impaired in Type II diabetes. We evaluated the pattern of enhancement by the potent incretin, glucagon...

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Главные авторы: Cunningham, Barbara A, Richard, Ann-Marie T, Dillon, Joseph S, Daley, Jennifer T, Civelek, Vildan N, Deeney, Jude T, Yaney, Gordon C, Corkey, Barbara E, Tornheim, Keith
Формат: Artigo
Язык:Inglês
Опубликовано: 2003
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223070/
https://ncbi.nlm.nih.gov/pubmed/12356335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021196
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