ロード中...

Ionizing radiation induces ataxia telangiectasia mutated kinase (ATM)-mediated phosphorylation of LKB1/STK11 at Thr-366.

The serine/threonine protein kinase LKB1 functions as a tumour suppressor, and mutations in this enzyme lead to the inherited Peutz-Jeghers cancer syndrome. We previously found that LKB1 was phosphorylated at Thr-366 in vivo, a residue conserved in mammalian, Xenopus and Drosophila LKB1, located on...

詳細記述

保存先:
書誌詳細
主要な著者: Sapkota, Gopal P, Deak, Maria, Kieloch, Agnieszka, Morrice, Nick, Goodarzi, Aaron A, Smythe, Carl, Shiloh, Yosef, Lees-Miller, Susan P, Alessi, Dario R
フォーマット: Artigo
言語:Inglês
出版事項: 2002
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223019/
https://ncbi.nlm.nih.gov/pubmed/12234250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021284
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!