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Translation initiation at non-AUG codons mediated by weakened association of eukaryotic initiation factor (eIF) 2 subunits.

The heterotrimeric eukaryotic initiation factor (eIF) 2 binds the initiator methionyl-tRNA in a GTP-dependent mode and delivers it to the 40 S ribosomal subunit. In the present study, we have identified amino acid residues in eIF2beta required for binding to eIF2gamma in yeast. Alteration of six res...

詳細記述

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書誌詳細
主要な著者: Hashimoto, Nilce N, Carnevalli, Larissa S, Castilho, Beatriz A
フォーマット: Artigo
言語:Inglês
出版事項: 2002
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222906/
https://ncbi.nlm.nih.gov/pubmed/12137565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020556
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