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Translation initiation at non-AUG codons mediated by weakened association of eukaryotic initiation factor (eIF) 2 subunits.

The heterotrimeric eukaryotic initiation factor (eIF) 2 binds the initiator methionyl-tRNA in a GTP-dependent mode and delivers it to the 40 S ribosomal subunit. In the present study, we have identified amino acid residues in eIF2beta required for binding to eIF2gamma in yeast. Alteration of six res...

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Detalhes bibliográficos
Main Authors: Hashimoto, Nilce N, Carnevalli, Larissa S, Castilho, Beatriz A
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222906/
https://ncbi.nlm.nih.gov/pubmed/12137565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020556
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