Sterol 14alpha-demethylase activity in Streptomyces coelicolor A3(2) is associated with an unusual member of the CYP51 gene family.

The annotation of the genome sequence of Streptomyces coelicolor A3(2) revealed a cytochrome P450 (CYP) resembling various sterol 14alpha-demethylases (CYP51). The putative CYP open reading frame (SC7E4.20) was cloned with a tetrahistidine tag appended to the C-terminus and expressed in Escherichia...

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Bibliografiske detaljer
Main Authors: Lamb, David C, Fowler, Kay, Kieser, Tobias, Manning, Nigel, Podust, Larissa M, Waterman, Michael R, Kelly, Diane E, Kelly, Steven L
Format: Artigo
Sprog:Inglês
Udgivet: 2002
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222601/
https://ncbi.nlm.nih.gov/pubmed/12023899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20011380
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