The human homologue of the yeast polyubiquitination factor Ufd2p is cleaved by caspase 6 and granzyme B during apoptosis.

In the present study, we demonstrate that a human homologue of Ufd2p (a yeast protein that catalyses the formation of long polyubiquitin chains, and is implicated in responses to environmental stress), UFD2 (ubiquitin fusion degradation protein-2), is cleaved during apoptosis induced by multiple sti...

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Bibliographic Details
Main Authors: Mahoney, James A, Odin, Joseph A, White, Sarah M, Shaffer, David, Koff, Andrew, Casciola-Rosen, Livia, Rosen, Antony
Format: Artigo
Language:Inglês
Published: 2002
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222341/
https://ncbi.nlm.nih.gov/pubmed/11802788
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