Polyubiquitinated Tristetraprolin Protects from TNF-induced, Caspase-mediated Apoptosis

Binding of TNF to its receptor (TNFR1) elicits the spatiotemporal assembly of two signaling complexes that coordinate the balance between cell survival and cell death. We have shown previously that, following TNF treatment, the mRNA decay protein tristetraprolin (TTP) is Lys-63-polyubiquitinated by...

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Bibliografiska uppgifter
Huvudupphovsmän: Resch, Ulrike, Cuapio, Angélica, Sturtzel, Caterina, Hofer, Erhard, de Martin, Rainer, Holper-Schichl, Yvonne M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2014
Ämnen:
Cell Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155675/
https://ncbi.nlm.nih.gov/pubmed/25056949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.563312
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