Polyubiquitinated Tristetraprolin Protects from TNF-induced, Caspase-mediated Apoptosis

Binding of TNF to its receptor (TNFR1) elicits the spatiotemporal assembly of two signaling complexes that coordinate the balance between cell survival and cell death. We have shown previously that, following TNF treatment, the mRNA decay protein tristetraprolin (TTP) is Lys-63-polyubiquitinated by...

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Bibliografiske detaljer
Main Authors: Resch, Ulrike, Cuapio, Angélica, Sturtzel, Caterina, Hofer, Erhard, de Martin, Rainer, Holper-Schichl, Yvonne M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2014
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155675/
https://ncbi.nlm.nih.gov/pubmed/25056949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.563312
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