Polyubiquitinated Tristetraprolin Protects from TNF-induced, Caspase-mediated Apoptosis

Binding of TNF to its receptor (TNFR1) elicits the spatiotemporal assembly of two signaling complexes that coordinate the balance between cell survival and cell death. We have shown previously that, following TNF treatment, the mRNA decay protein tristetraprolin (TTP) is Lys-63-polyubiquitinated by...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Resch, Ulrike, Cuapio, Angélica, Sturtzel, Caterina, Hofer, Erhard, de Martin, Rainer, Holper-Schichl, Yvonne M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2014
Gaiak:
Cell Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155675/
https://ncbi.nlm.nih.gov/pubmed/25056949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.563312
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