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Polyubiquitinated Tristetraprolin Protects from TNF-induced, Caspase-mediated Apoptosis

Binding of TNF to its receptor (TNFR1) elicits the spatiotemporal assembly of two signaling complexes that coordinate the balance between cell survival and cell death. We have shown previously that, following TNF treatment, the mRNA decay protein tristetraprolin (TTP) is Lys-63-polyubiquitinated by...

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Detalhes bibliográficos
Main Authors: Resch, Ulrike, Cuapio, Angélica, Sturtzel, Caterina, Hofer, Erhard, de Martin, Rainer, Holper-Schichl, Yvonne M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155675/
https://ncbi.nlm.nih.gov/pubmed/25056949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.563312
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