Caspase-2 Is Localized at the Golgi Complex and Cleaves Golgin-160 during Apoptosis

Caspases are an extended family of cysteine proteases that play critical roles in apoptosis. Animals deficient in caspases-2 or -3, which share very similar tetrapeptide cleavage specificities, exhibit very different phenotypes, suggesting that the unique features of individual caspases may account...

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Detalhes bibliográficos
Main Authors: Mancini, Marie, Machamer, Carolyn E., Roy, Sophie, Nicholson, Donald W., Thornberry, Nancy A., Casciola-Rosen, Livia A., Rosen, Antony
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2000
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174848/
https://ncbi.nlm.nih.gov/pubmed/10791974
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