Loading...
The intramembrane cleavage site of the amyloid precursor protein depends on the length of its transmembrane domain
Proteolytic processing of the amyloid precursor protein by β-secretase generates C99, which subsequently is cleaved by γ-secretase, yielding the amyloid β peptide (Aβ). This γ-cleavage occurs within the transmembrane domain (TMD) of C99 and is similar to the intramembrane cleavage of Notch. However,...
Na minha lista:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The National Academy of Sciences
2002
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC122196/ https://ncbi.nlm.nih.gov/pubmed/11805291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.032395699 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|