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Role of backbone solvation in determining thermodynamic β propensities of the amino acids

There is a paradox concerning the β propensities of the amino acids: the amino acids with the highest β propensities such as valine and isoleucine have the highest tendency to desolvate the peptide backbone, which should result in a loss of stability. Nevertheless, backbone solvation, calculated as...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Avbelj, Franc, Baldwin, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2002
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122186/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11805303/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.032665499
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