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Role of backbone solvation in determining thermodynamic β propensities of the amino acids

There is a paradox concerning the β propensities of the amino acids: the amino acids with the highest β propensities such as valine and isoleucine have the highest tendency to desolvate the peptide backbone, which should result in a loss of stability. Nevertheless, backbone solvation, calculated as...

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Autori principali: Avbelj, Franc, Baldwin, Robert L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC122186/
https://ncbi.nlm.nih.gov/pubmed/11805303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.032665499
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