Membrane-anchored metalloprotease MDC9 has an alpha-secretase activity responsible for processing the amyloid precursor protein.

MDC9, also known as meltrin gamma, is a membrane-anchored metalloprotease. MDC9 contains several distinct protein domains: a signal sequence followed by a prodomain and a domain showing sequence similarity to snake venom metalloproteases, a disintegrin-like domain, a cysteine-rich region, an epiderm...

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Detalhes bibliográficos
Main Authors: Koike, H, Tomioka, S, Sorimachi, H, Saido, T C, Maruyama, K, Okuyama, A, Fujisawa-Sehara, A, Ohno, S, Suzuki, K, Ishiura, S
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1220563/
https://ncbi.nlm.nih.gov/pubmed/10510302
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