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Metabolism of amyloid precursor protein in COS cells transfected with a β-secretase candidate
Thimet oligopeptidase (TOP) is a thiol- andmetallo-dependent peptidase and has been shown to beone of the β-secretase candidates. TOPexpressed in COS cells cleaved amyloid precursorprotein (APP) at the β-secretase site, and wefound a proteolytic product of APP called secretedform of APP by β-secreta...
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| Asıl Yazarlar: | , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Kluwer Academic Publishers
2000
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3466702/ https://ncbi.nlm.nih.gov/pubmed/19002828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1008119512341 |
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