Cationic liposome-encapsulated antisense oligonucleotide mediates efficient killing of intracellular Leishmania.

Antisense oligonucleotides have been considered as inhibitors of growth of intracellular parasites such as Leishmania, but only limited inhibition has been observed in vitro. We have encapsulated an antisense oligonucleotide, complementary to the Leishmania universal miniexon sequence, in cationic l...

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Bibliographic Details
Main Authors: Chakraborty, R, Dasgupta, D, Adhya, S, Basu, M K
Format: Artigo
Language:Inglês
Published: 1999
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1220262/
https://ncbi.nlm.nih.gov/pubmed/10333480
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