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Intracellular availability of unmodified, phosphorothioated and liposomally encapsulated oligodeoxynucleotides for antisense activity.

We have studied factors which may effect the intracellular availability of oligonucleotides to achieve antisense activity. 15-20 mer unmodified, phosphorothioate modified and liposomally encapsulated oligodeoxynucleotides have been tested in leukemia MOLT-3 cells. Phosphorothioate analogs penetrated...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Thierry, A R, Dritschilo, A
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1992
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC334404/
https://ncbi.nlm.nih.gov/pubmed/1454532
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