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Nucleocytoplasmic shuttling: a novel in vivo property of antisense phosphorothioate oligodeoxynucleotides

Phosphorothioate oligodeoxynucleotides (P=S ODNs) are frequently used as antisense agents to specifically interfere with the expression of cellular target genes. However, the cell biological properties of P=S ODNs are poorly understood. Here we show that P=S ODNs were able to continuously shuttle be...

詳細記述

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書誌詳細
主要な著者: Lorenz, Peter, Misteli, Tom, Baker, Brenda F., Bennett, C. Frank, Spector, David L.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2000
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC102511/
https://ncbi.nlm.nih.gov/pubmed/10606658
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