Nucleocytoplasmic shuttling: a novel in vivo property of antisense phosphorothioate oligodeoxynucleotides

Phosphorothioate oligodeoxynucleotides (P=S ODNs) are frequently used as antisense agents to specifically interfere with the expression of cellular target genes. However, the cell biological properties of P=S ODNs are poorly understood. Here we show that P=S ODNs were able to continuously shuttle be...

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Bibliografske podrobnosti

izdano v:	Nucleic Acids Res
Principais autores:	Lorenz, Peter, Misteli, Tom, Baker, Brenda F., Bennett, C. Frank, Spector, David L.
Format:	Artigo
Jezik:	Inglês
Izdano:	Oxford University Press 2000
Teme:	Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102511/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10606658/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.2.582
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