Intracellular availability of unmodified, phosphorothioated and liposomally encapsulated oligodeoxynucleotides for antisense activity.

We have studied factors which may effect the intracellular availability of oligonucleotides to achieve antisense activity. 15-20 mer unmodified, phosphorothioate modified and liposomally encapsulated oligodeoxynucleotides have been tested in leukemia MOLT-3 cells. Phosphorothioate analogs penetrated...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Thierry, A R, Dritschilo, A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1992
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC334404/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1454532/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.21.5691
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