Hypothesis: ceramide conditionally activates atypical protein kinases C, Raf-1 and KSR through binding to their cysteine-rich domains.

Ítems similars

• Specificity of cysteine-rich domains in diacylglycerol kinases and protein kinases C.
  per: Houssa, B, et al.
  Publicat: (1998)
• The Cysteine-Rich Regions of the Regulatory Domains of Raf and Protein Kinase C as Retinoid Receptors
  per: Hoyos, Beatrice, et al.
  Publicat: (2000)
• KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation
  per: Tran, Timothy H., et al.
  Publicat: (2021)
• Targeting cysteine rich C1 domain of Scaffold protein Kinase Suppressor of Ras (KSR) with anthocyanidins and flavonoids – a binding affinity characterization study
  per: Karthik, Dhananjayan, et al.
  Publicat: (2014)
• Molecular recognition of RAS/RAF complex at the membrane: Role of RAF cysteine-rich domain
  per: Travers, Timothy, et al.
  Publicat: (2018)