Hypothesis: ceramide conditionally activates atypical protein kinases C, Raf-1 and KSR through binding to their cysteine-rich domains.

Por van Blitterswijk, W J
Publicado em 1998

Rapid attenuation of receptor-induced diacylglycerol and phosphatidic acid by phospholipase D-mediated transphosphatidylation: formation of bisphosphatidic acid.

Por van Blitterswijk, W J, Hilkmann, H
Publicado em 1993

Specificity of cysteine-rich domains in diacylglycerol kinases and protein kinases C.

Por Houssa, B, van Blitterswijk, W J
Publicado em 1998

Consensus sequences for ATP-binding sites in protein kinases do not apply to diacylglycerol kinases.

Por Schaap, D, van der Wal, J, van Blitterswijk, W J
Publicado em 1994

Platelet-derived growth factor activation of mitogen-activated protein kinase depends on the sequential activation of phosphatidylcholine-specific phospholipase C, protein kinase C...

Por van Dijk, M C, Hilkmann, H, van Blitterswijk, W J
Publicado em 1997

Changes in concanavalin A-mediated agglutination of hormone-dependent mouse mammary tumour cells during serial transplantation.

Por Sluyser, M., van der Valk, M., van Blitterswijk, W. J.
Publicado em 1980

N-hexanoyl-sphingomyelin potentiates in vitro doxorubicin cytotoxicity by enhancing its cellular influx

Por Veldman, R J, Zerp, S, van Blitterswijk, W J, Verheij, M
Publicado em 2004

Phosphatidic acid activation of protein kinase C-zeta overexpressed in COS cells: comparison with other protein kinase C isotypes and other acidic lipids.

Por Limatola, C, Schaap, D, Moolenaar, W H, van Blitterswijk, W J
Publicado em 1994

Membrane fluidity, capping of cell-surface antigens and immune response in mouse leukaemia cells.

Por Hilgers, J., van der Sluis, P. J., van Blitterswijk, W. J., Emmelot, P.
Publicado em 1978

Diacylglycerol kinase theta is translocated and phosphoinositide 3-kinase-dependently activated by noradrenaline but not angiotensin II in intact small arteries.

Por Walker, A J, Draeger, A, Houssa, B, van Blitterswijk , W J, Ohanian, V, Ohanian, J
Publicado em 2001

Protein kinase C activation by acidic proteins including 14-3-3.

Por Van Der Hoeven, P C, Van Der Wal, J C, Ruurs, P, Van Blitterswijk, W J
Publicado em 2000

Diacylglycerol kinase is phosphorylated in vivo upon stimulation of the epidermal growth factor receptor and serine/threonine kinases, including protein kinase C-epsilon.

Por Schaap, D, van der Wal, J, van Blitterswijk, W J, van der Bend, R L, Ploegh, H L
Publicado em 1993

The biologically active phospholipid, lysophosphatidic acid, induces phosphatidylcholine breakdown in fibroblasts via activation of phospholipase D. Comparison with the response to...

Por van der Bend, R L, de Widt, J, van Corven, E J, Moolenaar, W H, van Blitterswijk, W J
Publicado em 1992

Identification of a putative membrane receptor for the bioactive phospholipid, lysophosphatidic acid.

Por van der Bend, R L, Brunner, J, Jalink, K, van Corven, E J, Moolenaar, W H, van Blitterswijk, W J
Publicado em 1992

Mitogenic action of lysophosphatidic acid and phosphatidic acid on fibroblasts. Dependence on acyl-chain length and inhibition by suramin.

Por van Corven, E J, van Rijswijk, A, Jalink, K, van der Bend, R L, van Blitterswijk, W J, Moolenaar, W H
Publicado em 1992

Diacylglycerol generated by exogenous phospholipase C activates the mitogen-activated protein kinase pathway independent of Ras- and phorbol ester-sensitive protein kinase C: depen...

Por van Dijk, M, Muriana, F J, van Der Hoeven, P C, de Widt, J, Schaap, D, Moolenaar, W H, van Blitterswijk, W J
Publicado em 1997

Lysophosphatidic acid-induced Ca2+ mobilization in human A431 cells: structure-activity analysis.

Por Jalink, K, Hengeveld, T, Mulder, S, Postma, F R, Simon, M F, Chap, H, van der Marel, G A, van Boom, J H, van Blitterswijk, W J, Moolenaar, W H
Publicado em 1995