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G-protein inhibition of phospholipase C-beta 1 in membranes: role of G-protein beta gamma subunits.
Rat liver plasma membranes reconstituted with bovine brain phospholipase C beta 1 (PLC- beta 1) exhibit a dual regulation of PLC- beta 1 activity by G-proteins. Guanosine 5'-[gamma-thio]triphosphate (GTP[S]; 0.1 nM) produced a 20-25% inhibition of PLC- beta 1 activity within 7 min of incubation...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
1996
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1217751/ https://ncbi.nlm.nih.gov/pubmed/8870665 |
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