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G-protein inhibition of phospholipase C-beta 1 in membranes: role of G-protein beta gamma subunits.

Rat liver plasma membranes reconstituted with bovine brain phospholipase C beta 1 (PLC- beta 1) exhibit a dual regulation of PLC- beta 1 activity by G-proteins. Guanosine 5'-[gamma-thio]triphosphate (GTP[S]; 0.1 nM) produced a 20-25% inhibition of PLC- beta 1 activity within 7 min of incubation...

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Detalles Bibliográficos
Autor Principal: Litosch, I
Formato: Artigo
Idioma:Inglês
Publicado: 1996
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1217751/
https://ncbi.nlm.nih.gov/pubmed/8870665
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