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Beta gamma subunits of GTP-binding proteins inhibit muscarinic receptor stimulation of phospholipase C.

This study examines the mechanism of guanine nucleotide-binding protein (G protein) coupling of receptors to phospholipase C. The Xenopus oocyte has a muscarinic receptor-activated Cl- current that is mediated by inositol 1,4,5-trisphosphate. Modulation of the muscarinic receptor-evoked Cl- current...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Moriarty, T M, Gillo, B, Carty, D J, Premont, R T, Landau, E M, Iyengar, R
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1988
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282607/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2461557/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.23.8865
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