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Beta gamma subunits of GTP-binding proteins inhibit muscarinic receptor stimulation of phospholipase C.
This study examines the mechanism of guanine nucleotide-binding protein (G protein) coupling of receptors to phospholipase C. The Xenopus oocyte has a muscarinic receptor-activated Cl- current that is mediated by inositol 1,4,5-trisphosphate. Modulation of the muscarinic receptor-evoked Cl- current...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1988
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282607/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2461557/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.23.8865 |
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