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Beta gamma subunits of GTP-binding proteins inhibit muscarinic receptor stimulation of phospholipase C.

This study examines the mechanism of guanine nucleotide-binding protein (G protein) coupling of receptors to phospholipase C. The Xenopus oocyte has a muscarinic receptor-activated Cl- current that is mediated by inositol 1,4,5-trisphosphate. Modulation of the muscarinic receptor-evoked Cl- current...

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Détails bibliographiques
Auteurs principaux: Moriarty, T M, Gillo, B, Carty, D J, Premont, R T, Landau, E M, Iyengar, R
Format: Artigo
Langue:Inglês
Publié: 1988
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC282607/
https://ncbi.nlm.nih.gov/pubmed/2461557
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