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Activation of phospholipase C beta 2 by the alpha and beta gamma subunits of trimeric GTP-binding protein.

Cotransfection assays were used to show that the members of the GTP-binding protein Gq class of alpha subunits could activate phospholipase C (PLC) beta 2. Similar experiments also demonstrated that G beta 1 gamma 1, G beta 1 gamma 5, and G beta 2 gamma 5 could activate the beta 2 isoform of PLC but...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Wu, D, Katz, A, Simon, M I
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1993
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46703/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8389480/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.11.5297
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