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Biosynthesis of the MUC2 mucin: evidence for a slow assembly of fully glycosylated units.

The human colonic cell line PC/AA was grown to near confluency over 24 days and labelled with [14C]proline and [3H]glucose over the last 48 h in culture. The cell layer was extracted with 6 M guanidinium chloride and the mature fully glycosylated mucins were isolated at a density of 1.45 g/ml by usi...

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Detalhes bibliográficos
Main Authors: Sheehan, J K, Thornton, D J, Howard, M, Carlstedt, I, Corfield, A P, Paraskeva, C
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1217261/
https://ncbi.nlm.nih.gov/pubmed/8645144
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