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The conformation of Alzheimer's beta peptide determines the rate of amyloid formation and its resistance to proteolysis.

Amyloid beta-peptide (A beta) is found in an aggregated poorly soluble form in senile or neuritic plaques deposited in the brain of individuals affected by Alzheimer's disease (AD). In addition soluble A beta (sA beta) is identified normally circulating in human body fluids. In this study we re...

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Detalhes bibliográficos
Main Authors: Soto, C, Castaño, E M
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1217103/
https://ncbi.nlm.nih.gov/pubmed/8670088
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