Large-Scale Single-Nucleotide Polymorphism (SNP) and Haplotype Analyses, Using Dense SNP Maps, of 199 Drug-Related Genes in 752 Subjects: the Analysis of the Association between Uncommon SNPs within Haplotype Blocks and the Haplotypes Constructed with Haplotype-Tagging SNPs

To optimize the strategies for population-based pharmacogenetic studies, we extensively analyzed single-nucleotide polymorphisms (SNPs) and haplotypes in 199 drug-related genes, through use of 4,190 SNPs in 752 control subjects. Drug-related genes, like other genes, have a haplotype-block structure,...

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Main Authors: Kamatani, Naoyuki, Sekine, Akihiro, Kitamoto, Takuya, Iida, Aritoshi, Saito, Susumu, Kogame, Akifumi, Inoue, Eisuke, Kawamoto, Manabu, Harigai, Masayoshi, Nakamura, Yusuke
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Human Genetics 2004
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1216054/
https://ncbi.nlm.nih.gov/pubmed/15202072
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