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Haplotype-based methods for detecting uncommon causal variants with common SNPs

Detecting uncommon causal variants (minor allele frequency (MAF) < 5%) is difficult with commercial single-nucleotide polymorphism (SNP) arrays that are designed to capture common variants (MAF > 5%). Haplotypes can provide insights into underlying linkage disequilibrium (LD) structure and can...

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Bibliografiske detaljer
Main Authors: Lin, Wan-Yu, Yi, Nengjun, Zhi, Degui, Zhang, Kui, Gao, Guimin, Tiwari, Hemant K., Liu, Nianjun
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3513398/
https://ncbi.nlm.nih.gov/pubmed/22706849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21650
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