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Haplotype-based methods for detecting uncommon causal variants with common SNPs
Detecting uncommon causal variants (minor allele frequency (MAF) < 5%) is difficult with commercial single-nucleotide polymorphism (SNP) arrays that are designed to capture common variants (MAF > 5%). Haplotypes can provide insights into underlying linkage disequilibrium (LD) structure and can...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3513398/ https://ncbi.nlm.nih.gov/pubmed/22706849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21650 |
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