Effects of p21(Cip1/Waf1) at Both the G(1)/S and the G(2)/M Cell Cycle Transitions: pRb Is a Critical Determinant in Blocking DNA Replication and in Preventing Endoreduplication

It has been proposed that the functions of the cyclin-dependent kinase inhibitors p21(Cip1/Waf1) and p27(Kip1) are limited to cell cycle control at the G(1)/S-phase transition and in the maintenance of cellular quiescence. To test the validity of this hypothesis, p21 was expressed in a diverse panel...

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Detalles Bibliográficos

Publicado en:	Mol Cell Biol
Principais autores:	Niculescu, Alexander B., Chen, Xinbin, Smeets, Monique, Hengst, Ludger, Prives, Carol, Reed, Steven I.
Formato:	Artigo
Idioma:	Inglês
Publicado:	Taylor & Francis 1998
Assuntos:	Cell Growth and Development
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC121530/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9418909/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.1.629
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