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Effects of p21(Cip1/Waf1) at Both the G(1)/S and the G(2)/M Cell Cycle Transitions: pRb Is a Critical Determinant in Blocking DNA Replication and in Preventing Endoreduplication

It has been proposed that the functions of the cyclin-dependent kinase inhibitors p21(Cip1/Waf1) and p27(Kip1) are limited to cell cycle control at the G(1)/S-phase transition and in the maintenance of cellular quiescence. To test the validity of this hypothesis, p21 was expressed in a diverse panel...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Niculescu, Alexander B., Chen, Xinbin, Smeets, Monique, Hengst, Ludger, Prives, Carol, Reed, Steven I.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 1998
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC121530/
https://ncbi.nlm.nih.gov/pubmed/9418909
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