Requirement for Phospholipase C-γ1 Enzymatic Activity in Growth Factor-Induced Mitogenesis
The cytoplasmic regions of the receptors for epidermal growth factor (EGF) and platelet-derived growth factor (PDGF) bind and activate phospholipase C-γ1 (PLC-γ1) and other signaling proteins in response to ligand binding outside the cell. Receptor binding by PLC-γ1 is a function of its SH2 domains...
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| Publicado no: | Mol Cell Biol |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC121526/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9418905/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.1.590 |
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