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Requirement for Phospholipase C-γ1 Enzymatic Activity in Growth Factor-Induced Mitogenesis

The cytoplasmic regions of the receptors for epidermal growth factor (EGF) and platelet-derived growth factor (PDGF) bind and activate phospholipase C-γ1 (PLC-γ1) and other signaling proteins in response to ligand binding outside the cell. Receptor binding by PLC-γ1 is a function of its SH2 domains...

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Bibliografski detalji
Izdano u:Mol Cell Biol
Glavni autori: Wang, Zhixiang, Glück, Stefan, Zhang, Lianfeng, Moran, Michael F.
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 1998
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC121526/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9418905/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.1.590
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