Requirement for Phospholipase C-γ1 Enzymatic Activity in Growth Factor-Induced Mitogenesis

The cytoplasmic regions of the receptors for epidermal growth factor (EGF) and platelet-derived growth factor (PDGF) bind and activate phospholipase C-γ1 (PLC-γ1) and other signaling proteins in response to ligand binding outside the cell. Receptor binding by PLC-γ1 is a function of its SH2 domains...

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Dades bibliogràfiques

Publicat a:	Mol Cell Biol
Autors principals:	Wang, Zhixiang, Glück, Stefan, Zhang, Lianfeng, Moran, Michael F.
Format:	Artigo
Idioma:	Inglês
Publicat:	Taylor & Francis 1998
Matèries:	Cell Growth and Development
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC121526/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9418905/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.1.590
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